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Database (2009) Vol. 2009:bap004; doi:10.1093/database/bap004 published on April 28, 2009
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Published by Oxford University Press 2009.
This is Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

The Homeodomain Resource: a comprehensive collection of sequence, structure, interaction, genomic and functional information on the homeodomain protein family

R. Travis Moreland{dagger}, Joseph F. Ryan{dagger}, Christopher Pan and Andreas D. Baxevanis*

Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA

*Corresponding author: Tel: +1 301 496 8570; Fax: +1 301 402 6858; Email: andy{at}nhgri.nih.gov


  Abstract

The Homeodomain Resource is a curated collection of sequence, structure, interaction, genomic and functional information on the homeodomain family. The current version builds upon previous versions by the addition of new, complete sets of homeodomain sequences from fully sequenced genomes, the expansion of existing curated homeodomain information and the improvement of data accessibility through better search tools and more complete data integration. This release contains 1534 full-length homeodomain-containing sequences, 93 experimentally derived homeodomain structures, 101 homeodomain protein–protein interactions, 107 homeodomain DNA-binding sites and 206 homeodomain proteins implicated in human genetic disorders.

Database URL: The Homeodomain Resource is freely available and can be accessed at http://research.nhgri.nih.gov/homeodomain/

Received November 7, 2008; Accepted March 14, 2009

{dagger}The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors.


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